Isibhedlele saseHeidelberg University

Uphengululo:Unyango lwe-aneurysm yengqondo yinkqubo yoqhaqho eyenziwa apho umngcipheko wokuqhekeka kwe-aneurysm uphakamileyo. Ububanzi obumiselweyo bokuhlala kwelinye ilizwe: iivekiIxesha elichithwe ekliniki lixhomekeka kuhlobo lwe-aneurysm. Nge-aneurysm engafakwanga mntu, ixesha lokubuyisela emva konyango lihlala lifutshane kunasemva kokuqhekeka.

I-acute lymphoblastic leukemia, ekwabizwa ngokuba yi-BONKE (ngokwamagama okuqala esi sifo), kwaye ngamanye amaxesha igama elinesi sifo esibuhlungu kakhulu sisifo esibuhlungu kakhulu kwinkqubo yehematopoietic. Isifo siqala kumongo wethambo. Umongo wethu wethambo ngumzi-mveliso weeseli zegazi ezahlukeneyo. Xa umongo wamathambo ugula, lo mzi-mveliso, endaweni yezempilo (ogqirha bathetha malunga neeseli ezivuthiweyo), uqalisa ukuvelisa inani elikhulu leeseli ezimhlophe zegazi ezingafakwanga.Xa umntu engaguli, ke zonke iiseli zegazi zikhula kwaye zihlaziywe ngokuvisisanayo, yonke into yenzeka ngendlela elungeleleneyo. Iiseli zegazi zivuthwa ngokuthe ngcembe, kwaye inkqubo yokuvuthwa intsokothile. Kodwa niniumntwana ugula sisifo se-lymphoblastic leukemia, i.e.BONKE, inkqubo yokuvuthwa iqhekeza ngokupheleleyo.Iiseli ezimhlophe zegazi, oko kukuthi, iiseli ezimhlophe zegazi, ziye ziyeke ukuvuthwa ngokupheleleyo kwaye zingakhuli zibe ziiseli ezisebenza ngokupheleleyo. Endaweni yoko, baqala ngokukhawuleza nokwabelana ngokungalawuleki. Umsebenzi wenkqubo ye-hematopoietic uyanda ukungasebenzi kakuhle: iiseli ezigulayo zigxotha ezi zisempilweni kwaye zithathe indawo yazo kumongo. Umntwana ogulayo akanazo iiseli ezimhlophe zegazi, iiseli ezibomvu zegazi (iiseli ezibomvu zegazi), okanye iiplatelets zegazi (iiplatelets).Yiyo loo nto abantwana bekhula ukuba ne-anemia (anemia), iingxaki ezahlukeneyo zosulelo (usulelo), kunye nokukopha rhoqo. Kwaye okuEzi ziimpawu zokuqala ezinokuthi zithethe malunga ne-leukemia ebukhali emntwaneni. Kodwa esi sifo ngokwaso, YONKE, ukusukela ekuqaleni asikho kwilungu elinye lomzimba. Ukusuka kumongo wethambo, ungena ungene egazini, ungene kwii-lymphoid tishu (inkqubo ye-lymphatic) kuwo onke amanye amalungu. Umsebenzi wayo yonke inkqubo yezitho, oko kukuthi, umzimba uphela, uqala ukuphazamiseka. Kungenxa yeso sizathu le nto, njengazo zonke ezinye iintlobo zesifo sokuvuvukala, sibizwa ngokuba sisifo esibuhlungu isifo, oko kukuthi, isifo sitshabalalisa umzimba wonke njengenkqubo.ZONKE zisasazeka emzimbeni wonke ngokukhawuleza. Ngaphandle konyango, iiseli ze-leukemia ziyahluka naphi na, hayiimiqobo yokuhlangana. Amalungu apho kuyekwe ukuba asebenze ngokuqhelekileyo kwaye izifo ezinkulu ezikhulu ziqala kuwo. Ukuba i-leukemia ayinyangwa, ke ukufa kwenzeka kwiinyanga ezimbalwa.Shiya isicelo sasimahla kwiwebhusayithi yethu kwaye iingcali zethu ziya kunxibelelana nawe kwaye zikuncede ukhethe ezona klinikhi zibalaseleyo kwimeko yakho. Indlela yokunyanga isifo se-leukemia esibuhlungu ixhomekeka kubudala nakwimeko yesigulana, uhlobo kunye nenqanaba lokuphuhliswa kwesi sifo, kwaye kuhlala kubalwa ngokukodwa kwimeko nganye.Zimbini iintlobo eziphambili zonyango lwe-leukemia ebukhali - ichemotherapy kunye nonyango lokunyanga - ukuhambisa umongo kumathambo.Chemotherapy yenziweamanyathelo amabini ngokulandelelana:Iinjongo zenqanaba lokuqala kukwenziwa koxolelo. Nge-chemotherapy, i-oncologists ifezekisa ukuncipha kwinqanaba leeseli eziqhumayo• Inqanaba lokudibanisa eliyimfuneko ukutshabalalisa iiseli zomhlaza eziseleUkuphinda ungeniswe, njengomthetho, ukuphindaphinda ngokupheleleyo inkqubo (iziyobisi, iidosi, frequency yezolawulo) zenqanaba lokuqalaUkongeza kumachiza e-chemotherapeutic, ii-cytostatics zikhona kwirejimeni yonyango ngokubanzi.Ngokwezibalo, ixesha elipheleleyo lonyango lwe-chemotherapy ye-leukemia ye-acute yiminyaka emi-2.Chemotherapy edityaniswa yi-cytostatics yiindlela yokubonakalisa ubukrakra, obangela inani leziphumo (isicaphucaphu, ukugabha, impilo enkenenkene, ukulahleka kweenwele, njl. njl.). Ukunciphisa imeko yesigulana, unyango oluhambelana nalo lumiselweyo. Ukongeza, kuxhomekeke kwimeko, amayeza okubulala iintsholongwane, i-detoxification agents, iplatelet kunye ne-erythrocyte ubunzima, kunye nokukhutshelwa kwegazi kunokucetyiswa.Ukufakelwa kwamathamboUkuhanjiswa kwamathambo kunika isigulana iiseli ezisempilweni, ezithi kamva zibe ngookhokho beeseli eziqhelekileyo zegazi.Eyona meko ibaluleke kakhulu yokufakelwa komnye umntu kukuxolelwa ngokupheleleyo kwesi sifo. Kubalulekile ukuba umongo wethambo ococwe kwiiseli eziqhekezayo ugcwaliswe kwakhona ziiseli ezisempilweni.Ukulungiselela isigulana utyando,Unyango lwe-immunosuppression olukhethekileyo lwenziwa. Oku kuyimfuneko ukutshabalalisa iiseli ze-leukemia kwaye kucinezele ukhuselo lomzimba ukunciphisa umngcipheko wokwaliwa.Unxibelelwano malunga nokutshintshwa komongo wamathambo:Ukwaphulwa kokusebenza kwamalungu angaphakathi• Izifo ezosulelayo ezingapheliyoUkuphinda uqalise kwi-leukemia ebukhali, engaguqukiyo ekuxolelweni• ukwaluphalaShiya isicelo kwiwebhusayithi yethu kwaye iingcali zethu ziya kunxibelelana nawe kwaye zikuncede ukhethe ezona klinikhi zibalaseleyo ngokubhekisele kwimeko yakho yasimahla.

Into yokuqala ekufuneka beyazi abaguli kunye nawo wonke umntu obhinqileyo malunga nomhlaza wamabele (njengoko, eneneni, malunga naluphi na uhlobo lomhlaza): namhlanje esi ayisosigwebo, isigaba sangaphambi sesi sifo, ayanda amathuba wokoyisa umhlaza ngokupheleleyo. Kwaye kwizigaba ezilandelayo, kukho amathuba ngakumbi okulwa nesi sifo ngokubulela kweendlela zonyango zangoku (jonga ngezantsi).Ngubani osengozini? Umhlaza webele sisifo esingalunganga esibi esenzeka phantse kumfazi omnye kwabalishumi. Umhlaza wesifuba unokufunyaniswa nangaliphi na ixesha, kodwa emva kweminyaka engama-65 ubudala, umngciphekoUkwenziwa kwethumba kukuphindwe kasi-6 kunangaphambili. Abaphandi bafumanisa ezona zinto zibangela ukukhula kwesi sifo:1) Ukufumana inzala: ukuba izalamane, ngakumbi kwicala loomama, ziye zafunyaniswa ukuba zinomhlaza webele, izitho zangasese zabasetyhini, kunye nezinye izifo ze-oncological, ke umngcipheko wokukhula komhlaza webele unyuke;2) ukuqala kokuqala kokuya esikhathini (ukuya kuthi ga kwiminyaka eli-12) kunye nokuqala kade kokuyeka ukuya esikhathini (emva kweminyaka engama-55);I-3) ukungabikho komntwana, ukuzala kade emva kwexesha (emva kweminyaka engama-30), ukunqongophala kokuzala okanye ixesha elifutshane lokuncancisa, isifo sokudumba kwasemva kokubeletha;4) ubomi besondo ngokungaqhelekanga;5) ukulimala kwe-mammary gland;I-6) Ukuchongwa kwe-"dishormonali-mammary gland hyperplasia ”;7) ukukhuluphala;8) ukungasebenzi kwe-thyroid;9) Unyango olungena endaweni yehomoni.Iimpawu zomhlaza wamabele Kwinkqubo yezonyango, ithumba elikwi-gland ye-mammary kwiimeko ezininzi lifunyaniswa ngumfazi okanye iqabane, okwenzekileyo. Isimila sinokufunyanwa xa kubhalwa uviwo lwe-mammologist, ugqirha wezifo zengqondo, okanye ugqirha ofumaneke ngengozi ngexesha lovavanyo.Zeziphi iimpawu ekufuneka ulumkise:    Ukongeza kwimvakalelo kwimfundo ebeleni, umfazi unokujonga utshintsho kwi-nipple: ulceration, retraction, spoting from the nipple. Eli lithuba lokudibana nodokotela kwangoko!     kumanqanaba kamva uphawuukukhula kobuthathaka, ukonakala kwempilo, ukukhohlela, ukuphefumla okunzima, iintlungu zamathambo zinokwenzeka.Unyango lomhlaza webele Unyango lomhlaza webele lwenziwa ngamanqanaba aliqela kusetyenziswa iindlela ezahlukeneyo. Iindlela ezintathu eziphambili zisetyenziswa namhlanje:Unyango lwe-antitumor yamayeza.Kukho iindlela ezahlukeneyo zonyango olunje, ezizezi:* ichemotherapy: kule meko, iziyobisi ezijolise ekutshatyalalisweni kweeseli ze-tumor zisetyenzisiwe;* Unyango lwehomoni, oko kukuthi, ukusetyenziswa kweziyobisi ezixinzelela umsebenzi wehomoni wesisu kunye nomzimba;* Unyango olujolisiweyo luhambo olutsha, indlela apho amachiza “abukhali” kwiziphumo ekujolise kuzo kwiseli yesisu kwaye enze ngokungacacanga kwimpiloizicubu zomntu;* I-Immunotherapy lulwalona lwalathiso lutsha, abathi namhlanje kwiingqungquthela zamazwe amaninzi ze-oncologists babizwe yenye yeendlela eziphambili nezikhuthazayo zokulwa iintlobo ezahlukeneyo zomhlaza. Umxholo we-immunotherapy ukwinkqubo ekhethekileyo yeeseli zomzimba zokuzikhusela. Ngenxa yetekhnoloji yabo eyahlukileyo, bajika baba sisixhobo esinamandla esikwaziyo nokutshabalalisa ngokuchanekileyo iiseli zomhlaza.Ngokuxilongwa komhlaza wamabele, unyango lokuhlinzwa kunye nonyango lweradiation luyasetyenziswa.Shiya isicelo kwiwebhusayithi yethu kwaye iingcali zethu ziya kunxibelelana nawe kwaye zikuncede ukhethe ezona klinikhi zibalaseleyo ngokubhekisele kwimeko yakho yasimahla.

Yintoni ekufuneka uyazi malunga nenkqubo yokufaka intsholongwane ukuba uthatha isigqibo sokuyenza IVF?Kwizibini ezininzi, i-IVF kuphela kwendlela yokuba nomntwana olindelwe kade. Ngaba le nkqubo yeyiphi na, ikhuselekile, ukulungiselela i-IVF kuhamba njani kwaye iyakubiza malini?Inqobo yenkqubo ye-IVFIVF yinkqubo yokuchumisa ngaphandle komzimba: amaqanda kunye nesidoda asuswe emzimbeni, isichumiso senzeka elabhoratri. Emva koko amaqanda achumileyo abekwa kwi-incubator kwiintsuku ezingama-5-6 kwaye kwinkqubo yokuhlukana atyalwe esibelekweni.Iimpawu zeukuqeshwaIVF iboniswa kwiimeko ezininzi zokungachumi: •apha ngasentla, ihlala incediswa yiteknoloji yokuncedisa.I-ICSI -singeniso sokwaluka kwesidoda kwiqanda kusetyenziswa inaliti ebanzi kakhulu. Kuqhutywa ukuba •iimeko zaselebhu. Isetyenziselwa ukuba ukukhuthaza kungaphumeleli. Ukuthintela ukuvuselelwa kwehomoni.Uncedo oluxhonyiweyo yitekhnoloji eyenza ukuba kufakwe umbungu kwisibeleko. Umbungu ujikelezwe yigobolondo elincinci, elitshabalalisa ngaphambi kokufakwa.Ukulungiselela i-IVF, kuqhuba inkqubo kunye nokubeka iliso emva kwe-IVFUkulungiselela i-IVF kuthatha malunga neeveki ezi-2-3 kwaye kubandakanya iimvavanyo kubo bobabini abatshati. Inkqubo ye-IVF ihlala ibandakanya: •nullUkuba i-IVF ayinikezi isiphumo esifunekayo, abanye abantu abatshatayo baphendukela kwiinkonzo zoomama abasaqalayo.Kwamanye amazwe, ubugqwetha buthintelwe ngumthetho, kodwa kukho amazwe apho u-surrogacy afuneka khona kakhulu, umzekelo, eKazakhstan.Namhlanje eRussia, Kazakhstan nakwamanye amazwe e-CIS, kuyenzeka ukuba kwenziwe i-IVF yasimahla nangaluphi na uhlobo lokuzala.Shiya isicelo kwiwebhusayithi yethu kwaye iingcali zethu ziya kunxibelelana nawe kwaye zikuncede ukhethe ezona klinikhi zibalaseleyo ngokubhekisele kwimeko yakho yasimahla.